Keflex Acne

Antibiotics have been used to treat acne for years, but many conventional ones are no longer effective. If this is the case, your doctor may prescribe cephalexin for acne treatment. Many skin care experts consider cephalexin the best drug for treating and preventing acne. Cephalexin is a bactericidal antibiotic, meaning that it kills the bacteria that contribute to the formation of the acne lesions and can also reduce fatty acids present in sebum that form pimples. So, how does cephalexin work to treat acne? Let’s take a look.

Cephalexin belongs to a class of antibiotics known as cephalosporins. It is a broad-spectrum oral medication used for treating bacterial infections. It interacts with the synthesis of the bacterial cell walls. It causes these cell walls to rupture and ultimately kills the bacteria.

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Bacterial infections are undeniably a danger to human health. Studies by Peterborough Regional College, UK examined the samples of 3 bacteria strains: Staphylococcus, E. coli and Bacillus megaterium when treated with 7 antibiotics: Ampicillin (AMP), Tetracycline (TET), Erythromycin (ERY), Chloramphenicol (C) Cephalexin (CN), Streptomycin (STR) and Doxycycline (O). The study concluded that Cephalexin has a significant effect on E. coli although further research is required. This graph showcases the current observation.

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Cephalexin, however, is effective only against bacterial infections and is not effective against viruses that cause a cold, the flu, etc. So, can cephalexin help treat acne?

Cephalexin is not a novel anti-bacterial drug. Dermatologists often prescribe it for treating skin infections. But can cephalexin be used for acne treatment?

Analyzed 93 subjects administered with cephalexin for acne treatment. About 84% of the participants in the study had tried various oral medications previously but saw no results. After the trial period, a staggering 78% of the patients displayed at least some improvement in their condition with the use of cephalexin. However, the results in this study took about 8 to 9 months to show significant improvement.

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Cephalexin is useful for treating acne and can be an excellent option for users who are not responding well to other medications. The drug can also effectively manage severe breakouts. In the next section, we will review how to safely use cephalexin.

You need to ingest cephalexin orally, generally after every 6 to 12 hours. The medicine may be taken with or without food. Continue the course for 7 to 14 days or as advised by your dermatologist.

In case you are using a cephalexin-based suspension, shake the bottle thoroughly before each use. Measure the dosage carefully with a measuring cup or spoon. Consume the liquid after every 6 to 12 hours. Follow these directions for 7 to 14 days or until the prescription lasts.

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As with any antibiotic, you need to practice care and caution while using cephalexin. Now that you know how to use the drug, follow the precautions shared below:

It is very unlikely that you may develop any side effects to cephalexin if you follow the precautions. That said, it is important to be aware of the side effects of cephalexin.

Allergies to cephalexin are extremely rare. It also does not cause any major side effects when taken as per the recommended dosage. Typical side effects of cephalexin (as per anecdotal evidence) include:

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These side effects usually may subside on their own. But consult your physician if they persist. Further, discontinue the use of cephalexin and seek immediate medical attention if you experience:

It is possible to overdose on cephalexin, which may cause intense nausea, diarrhea, vomiting, red/pink/dark brown urine, and debilitating pain in the stomach. Be mindful of the dosage.

While cephalexin is a relatively new drug, doxycycline has been the go-to medication for a while. Before committing to any medication, the following factors may be considered:

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Cephalexin is used to treat bacterial infections and as a preventive treatment for individuals without adequate wound healing capabilities. Doxycycline is also an anti-bacterial drug, but it can cover a broader list of conditions beyond acne and infections. It also may help treat conditions like anthrax

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XA contagious, sexually transmitted infection (STI) caused by bacteria that can be passed between sexual partners through unprotected sex. , relapsing fever, yaws, typhoid fever, Lyme disease

While they may have the same function of killing bacteria, both the drugs perform different functions. Cephalexin belongs to the cephalosporin group of antibiotics

Antibiotics Used To Treat Acne

XDrugs that help people with bacterial infections by destroying the bacteria and stopping their growth. . On the other hand, doxycycline is a tetracycline antibiotic. Consult your doctor to better understand the functions of each drug before making your choice.

While cephalexin is available as a tablet, capsule, and an oral suspension, doxycycline is available in the pill, delayed-release pill, and liquid suspension forms.

While the regular dosage of cephalexin for adults is 250 mg for six hours, in severe cases, cephalexin 500 mg may be prescribed for treating acne and severe infections. Dosage for children is limited to 25 to 100 mg for every kilogram of their body weight.

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The recommended dosage of doxycycline is about 100 mg twice for the first day, followed by 100 to 200 mg per day twice daily. The dosage depends on the individual’s condition. Consult your doctor for more information.

Cephalexin poses fewer side effects, which may take the form of diarrhea, vomiting, or cramping. In contrast, doxycycline may have more far-reaching effects. It may make your skin sensitive, interfere with the performance of barrier-based birth control methods, and lead to diarrhea to the effect of watery or bloody stools. However, only a small minority of patients experience side effects.

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Cephalexin does not majorly interact with other drugs. But it can reduce the effect of typhoid and BCG options. Doxycycline, on the other hand, interacts with a variety of medicines ranging from antacids (aluminum-, calcium-, or magnesium-based), warfarin-based blood thinners, barbiturates, phenytoin, penicillin, carbamazepine, contraceptives, etc.

Cephalexin / Keflex (cephalexin)

Cephalexin is generally considered safe during pregnancy. However, it is secreted by the milk ducts, and hence, lactating mothers should not consume it while breastfeeding their children. Consult your doctor for more information as research is limited in this regard.

Doxycycline may interfere with bone and teeth development in the growing fetus. It also may affect the well-being of both the mother and the child.

If you believe you have exhausted all possible options to treat acne, and are looking for alternatives, consult a dermatologist to tackle the underlying issue. They might ask you to use cephalexin, another acne treatment option. But how do you use it to treat acne? Check out the infographic below to learn more.

So Depressed By Acne

Cephalexin is an anti-bacterial drug that may have an important role in the management of acne. Whatever preliminary studies are available state that cephalexin could be a promising acne treatment. Despite its many advantages, it is an antibiotic drug, and the user must practice caution while consuming it. Be wary of its side effects and use it as prescribed by your dermatologist.

Amoxicillin is a commonly prescribed antibiotic for acne and is known to reduce inflammation. Cephalexin also showed better results in some instances. You must consult a doctor to understand which antibiotic may help relieve your acne as the results may depend on multiple factors, including acne severity, drug interaction, and overall health.

Since cephalexin and amoxicillin are two different antibiotics, their dosages may vary and are not comparable. Both are effective against multiple bacteria. Which antibiotic may work better on you depends on factors like the type of bacteria, the severity of the condition, and your medical history. Therefore, always consult a doctor before taking an antibiotic.

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Anecdotal evidence suggests that cephalexin usually takes 5-7 days to clear skin infections. It is a short-term treatment, and your skin may start showing improvement after the initial 2 to 3 days of consuming it. However, there are no relevant studies supporting these claims.

Yes, anecdotal evidence suggests that acne may come back after antibiotics usage if you stop consuming them before finishing the entire course of the medication. It is, for this reason, most health experts suggest completing your dosage even if your skin clears up within a few days.

Learn how to treat acne with antibiotics! Click on this informative video to find out the best methods to reduce breakouts and get clear skin.

Cephalexin: 8 Side Effects You Should Know About

Articles on are backed by verified information from peer-reviewed and academic research papers, reputed organizations, research institutions, and medical associations to ensure accuracy and relevance. Read our editorial policy to learn more.

Dr. Priya Gill is a consultant dermatologist in Klang, Malaysia, with over 16 years of experience. She specializes in the management of all medical and surgical dermatology issues and has a special interest in laser therapy and phototherapy. She has more than 25 publications in local and international journals to her name. She is passionate about public and patient education...more

Arshiya Syeda is a senior editor at with 7 years of experience. Prior to that, she was a content writer and combined her writing and research skills to write over 200 high-performing articles on hairstyles, hair care, and skin care. She holds a bachelor's degree in literature and psychology from Osmania University, Hyderabad, and a post-graduate diploma in psychological...more

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